I've been using a well known branded spray of the methylcobalamin b12 with great success for the past 6/7 years and was wondering if you'd consider the methylcobalamin form of vitamin b12 instead of the cyanocobalamin.
Also, apart from the cyanocobalamin form of B12 being more cost effective and the tablet kind supposedly easier to absorb, (I dispute this with my own personal experience), why have you chosen this type other than the methylcobalamin?
Research suggests that compared to tablet forms, sprays have a faster onset of action as they do not need to wait for dissolution. Furthermore, sprays allow for the vitamin to enter into the systemic circulation, bypassing the intestinal vessels. This reduces the amount of time between administration and absorption, which is typically longer when taking other oral forms such as tablets.
Any information would be much appreciated.
Hi, we chose Cyanocobalamin because it is reputed to have superior stability and there are some links (albeit limited) between Methylcobalamin and exacerbating skin breakouts. We are still researching B12 though, and working on new product versions. Spray forms are useful but require preservatives, as B12 is a water-soluble Vitamin, so we've been keen to avoid spray forms because we don't really want to use preservatives and have them follow the B12 into the bloodstream this way. We are hoping to have a new B12 product later in 2021 though, so watch this space....!
I noticed that the list of ingredients on the label on the Vitamin B12 bottle says: diglycerides of coconut fatty acid, cholecalciferol and D-alpha tocopherol, no indication of Cyanocobalamin. Is this correct? Cholecalciferol is Vitamin D indeed! Another question: why do you put magnesium stearate in the composition of vitamin D?
Hi, I think you must have an old label that inadvertently contained an inaccurate ingredient listing. The B12 listing is: "Microcrystalline cellulose, Hydroxypropylmethyl Cellulose, Cyanocobalamin, Anticaking agent (Magnesium Stearate)"
Absent any impaired absorption, age-related or otherwise, with a high dose oral B12 supplement one would in general expect to absorb (up to) 1-2 micrograms via intrinsic factor plus about 1% via passive diffusion. Do you have any data one how much B12 is absorbed (per tablet) with your specific, time release formulation? Thank you.
P.S.: For sustainability reasons, a greater than 60 tablets package size would be much appreciated- maybe also forgoing the plastic bottle completely.
Hi, it is difficult to give absolute figures as there are so many factors involved, however we do know the sustained release tablet format makes the B12 available for absorption over a 4-8 period, which gives the body a very good chance to absorb the vast majority of it. B12 is highly water-soluble and so the body takes what it requires with the rest safety excreted. Our current bottles are a sugar cane compound that is 100% biodegradable within 10 years.
Isn't 1000 mcg of b12 required for a week ? I read a lot that if you take one 1000 a day, it's for a short period of time only (15 days to 2 months) if you have a deficiency.
Hi, the body takes the B12 it requires and the rest is safety excreted. The reason we use a high dose in a sustained release tablet is to allow the body the best chance of getting the amount it requires. Once your B12 status normalises, it is correct that this level of B12 can be taken weekly rather than daily to maintain the status.
I am readily your customer. nevertheless can I know if your products been tested with any negative effects on the liver/kidney related pls?
Hi, all of the ingredients used in our products have been tested to ensure no such possible negative effects. We work to European Food Safety Authority (EFSA) regulations for our formulas and the levels of nutrients that we use.
I've been reading about vitamine B12 supplementation for my mother. We are both vegans but apparently she needs a lot more vit B12. I've read a recommendation of 50μg per day for the average adult and 1000μg for seniors. I've also read that you can overdose on vit B12. I was looking at your active energy supplement and it says you can combine it with the extra B12 supplement but that would mean you take 2000μg per day, I was wondering why you say you can take it together as this seems like a lot of B12?
Hi, it isn't the case that you can overdose on Vitamin B12. The body grabs what it needs and the rest passes safely through.
Que peso tiene 9 frascos de B12?
Hi, each bottle of Vitamin B12 weighs approximately 30g
If I take the multivitamin and mineral - veg vit, would there be any benefit in also taking the B12 sustained release tablet?
Our B12 sustained release tablet does offer a super strength, so it really depends if you are deficient in Vitamin B12 (and to what extent). There is a good level in VegVit already, so ordinarily I would say that is fine. Depending on your diet, it might be worth getting a B12 test done to see if you do need to take a higher level. From a safety perspective, there is no problem combining the two.
Does the vitamin B12 contain the same amount of B12 as the 'Active Energy Complex'? So there would be no need to take both?
Hi, yes that's correct. If you're taking Active Energy Complex, there is no need to take additional B12.
Peut-on coupé le cp en deux pour le donner à un enfant de 2ans (1000mcg/sem selon recommandation)?
Oui, vous pouvez couper le comprimé en deux pour cette dose requise.
Hi - Are you able to take your B12 under the tongue (ie. sublingual) until it dissolves? Or does it have to only be taken with a glass of water? Thank you.
Please swallow the B12 tablet as the structure is designed to slowly release over time in the stomach environment. That is important to benefit from the sustained release design.
Buongiorno! I vostri prodotti possono essere presi anche da un neonato di 6 mesi che fa pasti vegetariani? Grazie mille per la vostra gentile risposta!
We always recommend getting advice from Doctors before giving any supplements to children. Formula-wise, our B12 is fine for children from toddler age and upwards.
Can I ask where is this vitamin B12 extracted from?
We use Cyanocobalamin as it is the most stable form of vitamin B12 for a good shelf life.
I am surprised to see you use synthetic cyanocobalamin instead of the natural form methylcobalamin. My health provider has specifically stated to avoid this type as it is not considered a healthy form of B12. The synthetic form requires the body to remove the toxic cyanide molecule before it can convert and utilise the B12.
That said, my applied kinesiologist is able to test and see if my body needs a methylated or nonmethylated form or supplement at a given time. (Sometimes I have needed hydroxy- B vitamins, sometimes methlyated forms.)
"Although the amount of cyanide is considered toxicologically insignificant, humans must remove and detoxify the cyanide molecule, reduce the cobalamin to its usable +1 oxidation state, and then enzymatically convert the cobalamin into one of two metabolically active coenzyme forms. Nutritional inadequacies, enzyme defects, and pathological changes to tissues can all contribute to a reduced ability of the body to accomplish the synthesis of the active forms of vitamin B12 from CN-Cbl (Cyanocobalamin). Kelly, N.D., G. (1997). The Coenzyme Forms of Vitamin B12: Toward an Understanding of their Therapeutic Potential. Retrieved from
The general view in the Nutrition industry is that Cyanocobalamin is the superior variant of B12 versus Methylcobalamin. We sought a lot of advice, including from the Vegan Society's scientific experts. The Cyanocobalamin we use is produced through a fermentation method. It is more stable than Methylcobalamin, and doesn't have some of the reported negative skin effects reported.
The cyanide point needs perspective of levels. Many fruits and vegetables contain cyanide, which sounds horrific, but the levels are tiny and that is where we are. Our bodies are always ingesting small amounts of cyanide through our diets. If we (or food and nutritional regulators) had any concerns whatsoever, we wouldn't use it.
Mi hija de 8 años puede tomar la vitamina B12 en esta presentación?
Firstly we always recommend getting advice from Doctors before giving any supplements to children. Formula-wise, our B12 is fine for children from toddler age and upwards. The level of B12 is high (due to many people, particularly vegans and vegetarians, being deficient) but the body takes what it needs and excretes the rest so there is no issue of taking too much from our product.
Would it be a problem to take this Vitamin B12 product along with your VegVit multivitamin supplement?
Hi, it is fine from a safety-perspective to combine VegVit and our Vitamin B12 sustained release tablets
Do Vegans and Vegetarians need to supplement with Vitamin B12?
Yes, and particularly Vegans as it is not found in the Vegan diet nor in a typical Vegetarian diet.
What is the source of your Vitamin B12 and is it Vegan suitable?
Our Vitamin B12 is Vegan-suitable as it is produced using fermentation (think brewing beer, but less tasty!).
How do I take Vegetology Vitamin B12 tablets?
For best results, swallow 1 of our Vitamin B12 tablet with a glass of water. As with all supplements, please take it at a meal time. We recommend breakfast as the ideal time to take Vitamin B12, however it can be taken at any meal time during the day.
Can I chew the Vitamin B12 tablets?
No, please don't chew the tablets. They are designed to offer sustained release, and chewing will immediately break down the tablet and damage the sustained release effectiveness. The tablets are relatively small and easy to swallow with a glass of water.
Which form of B12 do you use?
We use B12 in the form of Cyanocobalamin.
I read that B12 can cause outbreaks / spots on the skin. Is that true?
There have been some links between B12 in the form of Methylcobalamin and spots, however we use B12 in the form of Cyanocobalamin and there are no such links.
How do you achieve sustained release?
We have constructed the tablet to break down at a slow rate over time, which ensures a constant release of the Vitamin B12 rather than a big single hit. We make our tablets as simple as possible to avoid the use of fillers.
Why is sustained release important for B12?
Vitamin B12 is a water-soluble Vitamin and the body takes what it needs with the rest excreted. This means that without a sustained release design, much of the high dose of Vitamin B12 can be lost if taken as a single 'hit'. Our special sustained release technology is highly beneficial for 2 reasons; firstly the B12 is released at a constant rate over 5-6 hours, ensuring longer-lasting benefits. Secondly, the sustained release prevents the body getting more than it needs in one single 'hit' and simply excreting (wasting) the majority of it.
Is “sustained release” the same as “timed release”?
Yes. Some regions refer to "timed release", which is the same thing.
Why use such a high dose of Vitamin B12?
The recommendations on doses of Vitamin B12 differ massively from person to person, based on a plethora of different considerations. Deficiency is a major issue across many demographics, not least Vegans and Vegetarians.As Vitamin B12 is a water-soluble Vitamin, the body takes what it needs, and the rest is excreted. Therefore a high dose is often recommended by Nutritionists and Health Practitioners so the body can recover from deficiency and benefit from as much B12 as it needs, with any surplus simply excreted.
Why take Vitamin B12?
Vitamin B12 plays vital roles in our body. It is important in the production of red blood cells and helps our body to convert food into energy. It is well known for its benefits to the nervous system, immune system and for fighting tiredness and fatigue.